Monomeric agonist peptide/MHCII complexes activate T‐cells in an autonomous fashion

Molecular crowding of agonist peptide/MHC class II complexes (pMHCIIs) with structurally similar, yet per se non‐stimulatory endogenous pMHCIIs is postulated to sensitize T‐cells for the recognition of single antigens on the surface of dendritic cells and B‐cells. When testing this premise with the...

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Detalles Bibliográficos
Autores principales: Platzer, René, Hellmeier, Joschka, Göhring, Janett, Perez, Iago Doel, Schatzlmaier, Philipp, Bodner, Clara, Focke‐Tejkl, Margarete, Schütz, Gerhard J, Sevcsik, Eva, Stockinger, Hannes, Brameshuber, Mario, Huppa, Johannes B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626418/
https://www.ncbi.nlm.nih.gov/pubmed/37768718
http://dx.doi.org/10.15252/embr.202357842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626418/
https://www.ncbi.nlm.nih.gov/pubmed/37768718
http://dx.doi.org/10.15252/embr.202357842

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