Cargando…

DONSON is required for CMG helicase assembly in the mammalian cell cycle

DONSON is one of 13 genes mutated in a form of primordial microcephalic dwarfism known as Meier‐Gorlin syndrome. The other 12 encode components of the CDC45‐MCM‐GINS helicase, around which the eukaryotic replisome forms, or are factors required for helicase assembly during DNA replication initiation...

Descripción completa

Detalles Bibliográficos
Autores principales: Evrin, Cecile, Alvarez, Vanesa, Ainsworth, Johanna, Fujisawa, Ryo, Alabert, Constance, Labib, Karim PM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626419/
https://www.ncbi.nlm.nih.gov/pubmed/37781960
http://dx.doi.org/10.15252/embr.202357677