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Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis

Effector cytotoxic T lymphocytes (CTLs) are critical for ridding the body of infected or cancerous cells. CTL T cell receptor (TCR) ligation not only drives the delivery and release of cytolytic granules but also initiates a new wave of transcription. In order to address whether TCR‐induced transcri...

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Detalles Bibliográficos
Autores principales: Richard, Arianne C, Ma, Claire Y, Marioni, John C, Griffiths, Gillian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626425/
https://www.ncbi.nlm.nih.gov/pubmed/37860838
http://dx.doi.org/10.15252/embr.202357653