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Antibody-recognizing residues 188-211 of TMEM106B exhibit immunohistochemical reactivity with the TMEM106B C-terminal fragment

Accumulation of TMEM106B fibrils composed of cleaved C-terminal fragments (CTF) of transmembrane protein 106B (TMEM106B) has recently been observed in the brains of elderly subjects and individuals with neurodegenerative diseases. To date, one antibody recognizing the residues 239-250 has been found...

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Detalles Bibliográficos
Autores principales: Ishikawa, Ruoyi, Yamazaki, Yu, Nakamori, Masahiro, Takahashi, Tetsuya, Maruyama, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626444/
https://www.ncbi.nlm.nih.gov/pubmed/37937069
http://dx.doi.org/10.3389/fnins.2023.1250547