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Local glucocorticoid synthesis regulates house dust mite-induced airway hypersensitivity in mice

BACKGROUND: Extra-adrenal glucocorticoid (GC) synthesis at epithelial barriers, such as skin and intestine, has been shown to be important in the local regulation of inflammation. However, the role of local GC synthesis in the lung is less well studied. Based on previous studies and the uncontentiou...

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Detalles Bibliográficos
Autores principales: Merk, Verena M., Phan, Truong San, Wiedmann, Alice, Hardy, Rowan S., Lavery, Gareth G., Brunner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626452/
https://www.ncbi.nlm.nih.gov/pubmed/37936704
http://dx.doi.org/10.3389/fimmu.2023.1252874