PRELP secreted from mural cells protects the function of blood brain barrier through regulation of endothelial cell-cell integrity

Introduction: Proline/arginine-rich end leucine-rich repeat protein (PRELP), is a small secreted proteoglycan expressed by pericytes and vascular smooth muscle cells surrounding the brain vasculature of adult mouse. Methods: We utilised a Prelp knockout (Prelp (−/−)) mouse model to interrogate vascu...

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Detalles Bibliográficos
Autores principales: Davaapil, Hongorzul, Hopkins, Jack, Bonnin, Nadia, Papadaki, Vasiliki, Leung, Alex, Kosuge, Hirofumi, Tashima, Takumi, Nakakido, Makoto, Sekido, Ryohei, Tsumoto, Kouhei, Sagoo, Mandeep S., Ohnuma, Shin-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626469/
https://www.ncbi.nlm.nih.gov/pubmed/37936982
http://dx.doi.org/10.3389/fcell.2023.1147625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626469/
https://www.ncbi.nlm.nih.gov/pubmed/37936982
http://dx.doi.org/10.3389/fcell.2023.1147625

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