4-nitroquinoline 1-oxide induces immune cells death to onset early immunosuppression during oral squamous cell carcinoma development

4-Nitroquinoline N-oxide (4-NQO) and its derivatives react with genomic DNA to form stable quinolone monoadducts, which are highly mutagenic and genotoxic. While the chronic high-dose exposure of epithelial cells to a carcinogen such as 4-NQO leads to tumor development, its effect on other cells has...

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Detalles Bibliográficos
Autores principales: Sahu, Satya Ranjan, Thakur, Shweta, Peroumal, Doureradjou, Utkalaja, Bhabasha Gyanadeep, Dutta, Abinash, Kumari, Premlata, Subhadarsini, Ipsita, Acharya, Narottam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626482/
https://www.ncbi.nlm.nih.gov/pubmed/37936711
http://dx.doi.org/10.3389/fimmu.2023.1274519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626482/
https://www.ncbi.nlm.nih.gov/pubmed/37936711
http://dx.doi.org/10.3389/fimmu.2023.1274519

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