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Saos‐2 cells cultured under hypoxia rapidly differentiate to an osteocyte‐like stage and support intracellular infection by Staphylococcus aureus

The intracellular infection of osteocytes represents a clinically important aspect of osteomyelitis. However, few human osteocyte in vitro models exist and the differentiation of immature osteoblasts to an osteocyte stage typically takes at least 4‐weeks of culture, making the study of this process...

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Detalles Bibliográficos
Autores principales: Zelmer, Anja R., Starczak, Yolandi, Solomon, Lucian B., Richter, Katharina, Yang, Dongqing, Atkins, Gerald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626491/
https://www.ncbi.nlm.nih.gov/pubmed/37929653
http://dx.doi.org/10.14814/phy2.15851