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Development of olanzapine solid dispersion by spray drying technique using screening design for solubility enhancement

INTRODUCTION: Olanzapine (OLZ) is a psychotropic class drug commonly used to treat schizophrenia, bipolar disorder, and acute manic episodes. It has less water solubility, resulting in a slow dissolution rate and oral bioavailability. Therefore, the development in oral dosage forms is required to en...

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Detalles Bibliográficos
Autores principales: Patil, Leena, Verma, Umakant, Rajput, Rahul, Patil, Pritam, Chaterjee, Aniruddha, Naik, Jitendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626510/
https://www.ncbi.nlm.nih.gov/pubmed/37937245
http://dx.doi.org/10.5599/admet.1998