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Development of olanzapine solid dispersion by spray drying technique using screening design for solubility enhancement
INTRODUCTION: Olanzapine (OLZ) is a psychotropic class drug commonly used to treat schizophrenia, bipolar disorder, and acute manic episodes. It has less water solubility, resulting in a slow dissolution rate and oral bioavailability. Therefore, the development in oral dosage forms is required to en...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Association of Physical Chemists
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626510/ https://www.ncbi.nlm.nih.gov/pubmed/37937245 http://dx.doi.org/10.5599/admet.1998 |