Native lamin A/C proteomes and novel partners from heart and skeletal muscle in a mouse chronic inflammation model of human frailty

Clinical frailty affects ∼10% of people over age 65 and is studied in a chronically inflamed (Interleukin-10 knockout; “IL10-KO”) mouse model. Frailty phenotypes overlap the spectrum of diseases (“laminopathies”) caused by mutations in LMNA. LMNA encodes nuclear intermediate filament proteins lamin...

Descripción completa

Detalles Bibliográficos
Autores principales: Elzamzami, Fatima D., Samal, Arushi, Arun, Adith S., Dharmaraj, Tejas, Prasad, Neeti R., Rendon-Jonguitud, Alex, DeVine, Lauren, Walston, Jeremy D., Cole, Robert N., Wilson, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626543/
https://www.ncbi.nlm.nih.gov/pubmed/37936983
http://dx.doi.org/10.3389/fcell.2023.1240285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626543/
https://www.ncbi.nlm.nih.gov/pubmed/37936983
http://dx.doi.org/10.3389/fcell.2023.1240285

Ejemplares similares