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Novel approach of prophylactic radiation to reduce toxicities comparing 2-step40 with 56-Gy simultaneous integrated boost intensity-modulated radiation therapy for locally advanced squamous cell carcinoma of the head and neck, an intergroup phase III trial (JCOG1912, NEW BRIDGE)

BACKGROUND: Chemoradiotherapy (CRT) with concurrent cisplatin is the standard of care as a nonsurgical definitive treatment for patients with locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN). However, CRT is associated with increased severe late adverse events, including swal...

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Detalles Bibliográficos
Autores principales: Yokota, Tomoya, Zenda, Sadamoto, Kodaira, Takeshi, Kiyota, Naomi, Fujimoto, Yasushi, Wasano, Koichiro, Takahashi, Ryo, Mizowaki, Takashi, Homma, Akihiro, Sasaki, Keita, Machida, Ryunosuke, Sekino, Yuta, Fukuda, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626703/
https://www.ncbi.nlm.nih.gov/pubmed/37932681
http://dx.doi.org/10.1186/s12885-023-11503-z