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Fabrication of a three-dimensional bone marrow niche-like acute myeloid Leukemia disease model by an automated and controlled process using a robotic multicellular bioprinting system

BACKGROUND: Acute myeloid leukemia (AML) is a hematological malignancy that remains a therapeutic challenge due to the high incidence of disease relapse. To better understand resistance mechanisms and identify novel therapies, robust preclinical models mimicking the bone marrow (BM) microenvironment...

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Detalles Bibliográficos
Autores principales: Alhattab, Dana M., Isaioglou, Ioannis, Alshehri, Salwa, Khan, Zainab N., Susapto, Hepi H., Li, Yanyan, Marghani, Yara, Alghuneim, Arwa A., Díaz-Rúa, Rubén, Abdelrahman, Sherin, AL-Bihani, Shuroug, Ahmed, Farid, Felimban, Raed I., Alkhatabi, Heba, Alserihi, Raed, Abedalthagafi, Malak, AlFadel, AlShaibani, Awidi, Abdalla, Chaudhary, Adeel Gulzar, Merzaban, Jasmeen, Hauser, Charlotte A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626721/
https://www.ncbi.nlm.nih.gov/pubmed/37932837
http://dx.doi.org/10.1186/s40824-023-00457-9