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Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia

BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent episodes of chronic intermittent hypoxia (CIH), which has been linked to the development of sympathoexcitation and hypertension. Furthermore, it has been shown that CIH induced inflammation and neuronal hyperactivation in the nu...

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Detalles Bibliográficos
Autores principales: Pereyra, Katherin, Las Heras, Alexandra, Toledo, Camilo, Díaz-Jara, Esteban, Iturriaga, Rodrigo, Del Rio, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626729/
https://www.ncbi.nlm.nih.gov/pubmed/37932867
http://dx.doi.org/10.1186/s40659-023-00463-0