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Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia
BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent episodes of chronic intermittent hypoxia (CIH), which has been linked to the development of sympathoexcitation and hypertension. Furthermore, it has been shown that CIH induced inflammation and neuronal hyperactivation in the nu...
Autores principales: | Pereyra, Katherin, Las Heras, Alexandra, Toledo, Camilo, Díaz-Jara, Esteban, Iturriaga, Rodrigo, Del Rio, Rodrigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626729/ https://www.ncbi.nlm.nih.gov/pubmed/37932867 http://dx.doi.org/10.1186/s40659-023-00463-0 |
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