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Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathway

BACKGROUND: Exposure to cytotoxic chemotherapy treatment may alter DNA methylation (DNAm) in breast cancer patients. METHODS: We performed DNAm analysis in 125 breast cancer patients with blood drawn before and after chemotherapy, using the Illumina MethylationEPIC array. DNAm changes of 588,798 ind...

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Detalles Bibliográficos
Autores principales: Ho, Peh Joo, Khng, Alexis Jiaying, Tan, Benita Kiat-Tee, Lim, Geok Hoon, Tan, Su-Ming, Tan, Veronique Kiak Mien, Tan, Ryan Shea Ying Cong, Lim, Elaine Hsuen, Iau, Philip Tsau-Choong, Chew, Ying Jia, Lim, Yi Ying, Hartman, Mikael, Tan, Ern Yu, Li, Jingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626732/
https://www.ncbi.nlm.nih.gov/pubmed/37932858
http://dx.doi.org/10.1186/s13058-023-01730-4