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Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathway
BACKGROUND: Exposure to cytotoxic chemotherapy treatment may alter DNA methylation (DNAm) in breast cancer patients. METHODS: We performed DNAm analysis in 125 breast cancer patients with blood drawn before and after chemotherapy, using the Illumina MethylationEPIC array. DNAm changes of 588,798 ind...
Autores principales: | Ho, Peh Joo, Khng, Alexis Jiaying, Tan, Benita Kiat-Tee, Lim, Geok Hoon, Tan, Su-Ming, Tan, Veronique Kiak Mien, Tan, Ryan Shea Ying Cong, Lim, Elaine Hsuen, Iau, Philip Tsau-Choong, Chew, Ying Jia, Lim, Yi Ying, Hartman, Mikael, Tan, Ern Yu, Li, Jingmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626732/ https://www.ncbi.nlm.nih.gov/pubmed/37932858 http://dx.doi.org/10.1186/s13058-023-01730-4 |
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