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How is overall survival assessed in randomised clinical trials in cancer and are subsequent treatment lines considered? A systematic review

BACKGROUND: Overall survival is the “gold standard” endpoint in cancer clinical trials. It plays a key role in determining the clinical- and cost-effectiveness of a new intervention and whether it is recommended for use in standard of care. The assessment of overall survival usually requires trial p...

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Detalles Bibliográficos
Autores principales: Royle, Kara-Louise, Meads, David, Visser-Rogers, Jennifer K., White, Ian R., Cairns, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626781/
https://www.ncbi.nlm.nih.gov/pubmed/37926806
http://dx.doi.org/10.1186/s13063-023-07730-1