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Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer
Structural tailoring of the flavone framework (position 7) via organopalladium-catalyzed C–C bond formation was attempted in this study. The impact of substituents with varied electronic effects (phenyl ring, position 2 of the benzopyran scaffold) on the antitumor properties was also assessed. Resul...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627047/ https://www.ncbi.nlm.nih.gov/pubmed/37919954 http://dx.doi.org/10.1080/14756366.2023.2276665 |