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Safety and immunogenicity of three dose levels of an investigational, highly purified Vero cell rabies vaccine: A randomized, controlled, observer-blinded, Phase II study with a simulated post-exposure regimen in healthy adults

A serum-free, highly purified rabies vaccine produced in Vero cells is under development. The initial formulation, PVRV-NG, was evaluated in five Phase II studies and subsequently reformulated (PVRV-NG2). This multicenter, observer-blinded Phase II study investigated the safety and immune response o...

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Detalles Bibliográficos
Autores principales: Pichon, Sylvie, Guinet-Morlot, Francoise, Saleh, Jamshid, Essink, Brandon, Pineda-Peña, Andrea-Clemencia, Moureau, Annick, Petit, Celine, Minutello, Ada-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627063/
https://www.ncbi.nlm.nih.gov/pubmed/37921410
http://dx.doi.org/10.1080/21645515.2023.2275453