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Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research

Background: Elucidating epigenetic mechanisms could provide new biomarkers for disease diagnosis and prognosis. Technological advances allow genome-wide profiling of 5-hydroxymethylcytosines (5hmC) in liquid biopsies. 5hmC-Seal followed by NGS is a highly sensitive technique for 5hmC biomarker disco...

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Detalles Bibliográficos
Autores principales: Gao, Lu, Zhang, Zhou, Cui, Xiao-Long, West-Szymanski, Diana, Ye, Chang, He, Chuan, Zhang, Wei, Bissonnette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627064/
https://www.ncbi.nlm.nih.gov/pubmed/37898998
http://dx.doi.org/10.1080/15592294.2023.2271692