Cargando…

Direct antitumoral effects of sulfated fucans isolated from echinoderms: a possible role of neuropilin-1/β1 integrin endocytosis and focal adhesion kinase degradation

Hypercoagulability, a major complication of metastatic cancers, has usually been treated with heparins from natural sources, or with their synthetic derivatives, which are under intense investigation in clinical oncology. However, the use of heparin has been challenging for patients with risk of sev...

Descripción completa

Detalles Bibliográficos
Autores principales: Lima, Antonio G F, Mignone, Viviane W, Vardiero, Francisco, Kozlowski, Eliene O, Fernandes, Laila R, Motta, Juliana M, Pavão, Mauro S G, Figueiredo, Camila C, Mourão, Paulo A S, Morandi, Verônica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627248/
https://www.ncbi.nlm.nih.gov/pubmed/37289485
http://dx.doi.org/10.1093/glycob/cwad044