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Direct antitumoral effects of sulfated fucans isolated from echinoderms: a possible role of neuropilin-1/β1 integrin endocytosis and focal adhesion kinase degradation
Hypercoagulability, a major complication of metastatic cancers, has usually been treated with heparins from natural sources, or with their synthetic derivatives, which are under intense investigation in clinical oncology. However, the use of heparin has been challenging for patients with risk of sev...
Autores principales: | Lima, Antonio G F, Mignone, Viviane W, Vardiero, Francisco, Kozlowski, Eliene O, Fernandes, Laila R, Motta, Juliana M, Pavão, Mauro S G, Figueiredo, Camila C, Mourão, Paulo A S, Morandi, Verônica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627248/ https://www.ncbi.nlm.nih.gov/pubmed/37289485 http://dx.doi.org/10.1093/glycob/cwad044 |
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