Nanopore-based direct sequencing of RNA transcripts with 10 different modified nucleotides reveals gaps in existing technology

RNA undergoes complex posttranscriptional processing including chemical modifications of the nucleotides. The resultant-modified nucleotides are an integral part of RNA sequences that must be considered in studying the biology of RNA and in the design of RNA therapeutics. However, the current “RNA-s...

Descripción completa

Detalles Bibliográficos
Autores principales: Burdick, Joshua T, Comai, Annelise, Bruzel, Alan, Sun, Guangxin, Dedon, Peter C, Cheung, Vivian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Software and Data Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627276/
https://www.ncbi.nlm.nih.gov/pubmed/37655917
http://dx.doi.org/10.1093/g3journal/jkad200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627276/
https://www.ncbi.nlm.nih.gov/pubmed/37655917
http://dx.doi.org/10.1093/g3journal/jkad200

Ejemplares similares