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Nanopore-based direct sequencing of RNA transcripts with 10 different modified nucleotides reveals gaps in existing technology
RNA undergoes complex posttranscriptional processing including chemical modifications of the nucleotides. The resultant-modified nucleotides are an integral part of RNA sequences that must be considered in studying the biology of RNA and in the design of RNA therapeutics. However, the current “RNA-s...
Autores principales: | Burdick, Joshua T, Comai, Annelise, Bruzel, Alan, Sun, Guangxin, Dedon, Peter C, Cheung, Vivian G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627276/ https://www.ncbi.nlm.nih.gov/pubmed/37655917 http://dx.doi.org/10.1093/g3journal/jkad200 |
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