Model Organism Modifier (MOM): a user-friendly Galaxy workflow to detect modifiers from genome sequencing data using Caenorhabditis elegans

Genetic modifiers are variants modulating phenotypic outcomes of a primary detrimental variant. They contribute to rare diseases phenotypic variability, but their identification is challenging. Genetic screening with model organisms is a widely used method for demystifying genetic modifiers. Forward...

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Detalles Bibliográficos
Autores principales: Maroilley, Tatiana, Rahit, K M Tahsin Hassan, Chida, Afiya Razia, Cotra, Filip, Rodrigues Alves Barbosa, Victoria, Tarailo-Graovac, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Software and Data Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627290/
https://www.ncbi.nlm.nih.gov/pubmed/37585487
http://dx.doi.org/10.1093/g3journal/jkad184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627290/
https://www.ncbi.nlm.nih.gov/pubmed/37585487
http://dx.doi.org/10.1093/g3journal/jkad184

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