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DELFOS—drug efficacy leveraging forked and specialized networks—benchmarking scRNA-seq data in multi-omics-based prediction of cancer sensitivity

MOTIVATION: Cancer is currently one of the most notorious diseases, with over 1 million deaths in the European Union alone in 2022. As each tumor can be composed of diverse cell types with distinct genotypes, cancer cells can acquire resistance to different compounds. Moreover, anticancer drugs can...

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Detalles Bibliográficos
Autores principales: Piochi, Luiz Felipe, Preto, António J, Moreira, Irina S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627353/
https://www.ncbi.nlm.nih.gov/pubmed/37862234
http://dx.doi.org/10.1093/bioinformatics/btad645