B Cells from Aged Mice Do Not Have Intrinsic Defects in Affinity Maturation in Response to Immunization

Affinity maturation, the progressive increase in serum Ab affinity after vaccination, is an essential process that contributes to an effective humoral response against vaccines and infections. Germinal centers are key for affinity maturation, because they are where B cells undergo somatic hypermutat...

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Detalles Bibliográficos
Autores principales: Lee, Jia Le, Innocentin, Silvia, Silva-Cayetano, Alyssa, Guillaume, Stephane M., Linterman, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Immunotherapy and Vaccines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627434/
https://www.ncbi.nlm.nih.gov/pubmed/37756528
http://dx.doi.org/10.4049/jimmunol.2300318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627434/
https://www.ncbi.nlm.nih.gov/pubmed/37756528
http://dx.doi.org/10.4049/jimmunol.2300318

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