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Comparative single-cell transcriptomic analysis of primate brains highlights human-specific regulatory evolution

Enhanced cognitive function in humans is hypothesized to result from cortical expansion and increased cellular diversity. However, the mechanisms that drive these phenotypic innovations remain poorly understood, in part because of the lack of high-quality cellular resolution data in human and non-hu...

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Detalles Bibliográficos
Autores principales: Suresh, Hamsini, Crow, Megan, Jorstad, Nikolas, Hodge, Rebecca, Lein, Ed, Dobin, Alexander, Bakken, Trygve, Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627823/
https://www.ncbi.nlm.nih.gov/pubmed/37667001
http://dx.doi.org/10.1038/s41559-023-02186-7