Adipocyte lipolysis protects mice against Trypanosoma brucei infection

Trypanosoma brucei causes African trypanosomiasis, colonizing adipose tissue and inducing weight loss. Here we investigated the molecular mechanisms responsible for adipose mass loss and its impact on disease pathology. We found that lipolysis is activated early in infection. Mice lacking B and T ly...

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Detalles Bibliográficos
Autores principales: Machado, Henrique, Hofer, Peter, Zechner, Rudolf, Smith, Terry K., Figueiredo, Luísa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627827/
https://www.ncbi.nlm.nih.gov/pubmed/37828246
http://dx.doi.org/10.1038/s41564-023-01496-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627827/
https://www.ncbi.nlm.nih.gov/pubmed/37828246
http://dx.doi.org/10.1038/s41564-023-01496-7

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