CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice

AIMS/HYPOTHESIS: Colony stimulating factor 1 (CSF1) promotes the proliferation, differentiation and survival of macrophages, which have been implicated in both beneficial and detrimental effects on glucose metabolism. However, the physiological role of CSF1 signalling in glucose homeostasis and the...

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Detalles Bibliográficos
Autores principales: Bosch, Angela J. T., Keller, Lena, Steiger, Laura, Rohm, Theresa V., Wiedemann, Sophia J., Low, Andy J. Y., Stawiski, Marc, Rachid, Leila, Roux, Julien, Konrad, Daniel, Wueest, Stephan, Tugues, Sonia, Greter, Melanie, Böni-Schnetzler, Marianne, Meier, Daniel T., Cavelti-Weder, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627931/
https://www.ncbi.nlm.nih.gov/pubmed/37792013
http://dx.doi.org/10.1007/s00125-023-06007-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627931/
https://www.ncbi.nlm.nih.gov/pubmed/37792013
http://dx.doi.org/10.1007/s00125-023-06007-1

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