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The proper timing of Atoh1 expression is pivotal for hair cell subtype differentiation and the establishment of inner ear function

Atoh1 overexpression is essential for hair cell (HC) regeneration in the sensory epithelium of mammalian auditory and vestibular organs. However, Atoh1 overexpression alone cannot induce fully mature and functional HCs in the mammalian inner ear. In the current study, we investigated the effect of A...

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Detalles Bibliográficos
Autores principales: You, Dan, Ni, Wenli, Huang, Yikang, Zhou, Qin, Zhang, Yanping, Jiang, Tao, Chen, Yan, Li, Wenyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628023/
https://www.ncbi.nlm.nih.gov/pubmed/37930405
http://dx.doi.org/10.1007/s00018-023-04947-w