Acidified drinking water improves motor function, prevents tremors and changes disease trajectory in Cln2(R207X) mice, a model of late infantile Batten disease

Batten disease is a group of mostly pediatric neurodegenerative lysosomal storage disorders caused by mutations in the CLN1–14 genes. We have recently shown that acidified drinking water attenuated neuropathological changes and improved motor function in the Cln1(R151X) and Cln3(−/−) mouse models of...

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Detalles Bibliográficos
Autores principales: Kovács, Attila D., Gonzalez Hernandez, Jose L., Pearce, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628098/
https://www.ncbi.nlm.nih.gov/pubmed/37932327
http://dx.doi.org/10.1038/s41598-023-46283-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628098/
https://www.ncbi.nlm.nih.gov/pubmed/37932327
http://dx.doi.org/10.1038/s41598-023-46283-w

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