Insights adjusting for non-adherence in randomized clinical trials: a reanalysis of an adjuvant trial of tamoxifen duration in early breast cancer

BACKGROUND: Several randomized clinical trials provide evidence of the survival benefit of extended adjuvant tamoxifen in women with estrogen receptor (ER)-positive early breast cancer (BC). However, non-adherence may lead to underestimate treatment effects using intention to treat (ITT) methods. We...

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Detalles Bibliográficos
Autores principales: Giudici, Fabiola, Pistilli, Barbara, Vaz-Luis, Ines, Karimi, Maryam, Delaloge, Suzette, Bachelot, Thomas, Michiels, Stefan, Bardet, Aurelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628101/
https://www.ncbi.nlm.nih.gov/pubmed/37697030
http://dx.doi.org/10.1038/s41416-023-02420-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628101/
https://www.ncbi.nlm.nih.gov/pubmed/37697030
http://dx.doi.org/10.1038/s41416-023-02420-w

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