Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2

Hydroxycarboxylic acid receptors (HCAR1, HCAR2, and HCAR3) transduce G(i/o) signaling upon biding to molecules such as lactic acid, butyric acid and 3-hydroxyoctanoic acid, which are associated with lipolytic and atherogenic activity, and neuroinflammation. Although many reports have elucidated the...

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Detalles Bibliográficos
Autores principales: Park, Jae-Hyun, Kawakami, Kouki, Ishimoto, Naito, Ikuta, Tatsuya, Ohki, Mio, Ekimoto, Toru, Ikeguchi, Mitsunori, Lee, Dong-Sun, Lee, Young-Ho, Tame, Jeremy R. H., Inoue, Asuka, Park, Sam-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628104/
https://www.ncbi.nlm.nih.gov/pubmed/37932263
http://dx.doi.org/10.1038/s41467-023-42764-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628104/
https://www.ncbi.nlm.nih.gov/pubmed/37932263
http://dx.doi.org/10.1038/s41467-023-42764-8

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