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Differential effects of interleukin-17A and 17F on cell interactions between immune cells and stromal cells from synovium or skin

We compared the contribution of IL-17A and IL-17F in co-culture systems mimicking cell interactions as found in inflamed synovium and skin. Synoviocytes or skin fibroblasts were co-cultured with activated PBMC, with IL-17A, IL-17 A/F, IL-17F, IL-23, anti-IL-17A, anti-IL-17A/F or anti-IL-17F antibodi...

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Detalles Bibliográficos
Autores principales: Tout, Issam, Noack, Mélissa, Miossec, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628108/
https://www.ncbi.nlm.nih.gov/pubmed/37932356
http://dx.doi.org/10.1038/s41598-023-45653-8