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Impact of germline DNA repair gene variants on prognosis and treatment of men with advanced prostate cancer

The clinical importance of germline variants in DNA repair genes (DRGs) is becoming increasingly recognized, but their impact on advanced prostate cancer prognosis remains unclear. A cohort of 221 newly diagnosed metastatic castration-resistant prostate cancer (mCRPC) patients were screened for path...

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Detalles Bibliográficos
Autores principales: Hansen, Emma B., Karlsson, Questa, Merson, Susan, Wakerell, Sarah, Rageevakumar, Reshma, Jensen, Jørgen B., Borre, Michael, Kote-Jarai, Zsofia, Eeles, Rosalind A., Sørensen, Karina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628129/
https://www.ncbi.nlm.nih.gov/pubmed/37932350
http://dx.doi.org/10.1038/s41598-023-46323-5