Cargando…

Tracing cancer evolution and heterogeneity using Hi-C

Chromosomal rearrangements can initiate and drive cancer progression, yet it has been challenging to evaluate their impact, especially in genetically heterogeneous solid cancers. To address this problem we developed HiDENSEC, a new computational framework for analyzing chromatin conformation capture...

Descripción completa

Detalles Bibliográficos
Autores principales: Erdmann-Pham, Dan Daniel, Batra, Sanjit Singh, Turkalo, Timothy K., Durbin, James, Blanchette, Marco, Yeh, Iwei, Shain, Hunter, Bastian, Boris C., Song, Yun S., Rokhsar, Daniel S., Hockemeyer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628133/
https://www.ncbi.nlm.nih.gov/pubmed/37932252
http://dx.doi.org/10.1038/s41467-023-42651-2