Evaluation of optimal methods and ancestries for calculating polygenic risk scores in East Asian population

Polygenic risk scores (PRSs) have been studied for predicting human diseases, and various methods for PRS calculation have been developed. Most PRS studies to date have focused on European ancestry, and the performance of PRS has not been sufficiently assessed in East Asia. Herein, we evaluated the...

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Detalles Bibliográficos
Autores principales: Kim, Dong Jun, Kang, Joon Ho, Kim, Ji-Woong, Cheon, Myeong Jae, Kim, Sun bin, Lee, Young Kee, Lee, Byung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628155/
https://www.ncbi.nlm.nih.gov/pubmed/37932343
http://dx.doi.org/10.1038/s41598-023-45859-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628155/
https://www.ncbi.nlm.nih.gov/pubmed/37932343
http://dx.doi.org/10.1038/s41598-023-45859-w

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