Cargando…
Evaluation of optimal methods and ancestries for calculating polygenic risk scores in East Asian population
Polygenic risk scores (PRSs) have been studied for predicting human diseases, and various methods for PRS calculation have been developed. Most PRS studies to date have focused on European ancestry, and the performance of PRS has not been sufficiently assessed in East Asia. Herein, we evaluated the...
Autores principales: | Kim, Dong Jun, Kang, Joon Ho, Kim, Ji-Woong, Cheon, Myeong Jae, Kim, Sun bin, Lee, Young Kee, Lee, Byung-Chul |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628155/ https://www.ncbi.nlm.nih.gov/pubmed/37932343 http://dx.doi.org/10.1038/s41598-023-45859-w |
Ejemplares similares
-
Polygenic risk score prediction of multiple sclerosis in individuals of South Asian ancestry
por: Breedon, Joshua R, et al.
Publicado: (2023) -
On cross-ancestry cancer polygenic risk scores
por: Fritsche, Lars G., et al.
Publicado: (2021) -
Optimal strategies for learning multi-ancestry polygenic scores vary across traits
por: Lehmann, Brieuc, et al.
Publicado: (2023) -
Polygenic Risk Score Improves Cataract Prediction in East Asian Population
por: Hsu, Chih-Chien, et al.
Publicado: (2022) -
NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
por: Thomas, Claire E., et al.
Publicado: (2022)