Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19

The role of host genetic factors in COVID-19 outcomes remains unclear despite various genome-wide association studies (GWAS). We annotate all significant variants and those variants in high LD (R(2) > 0.8) from the COVID-19 host genetics initiative (HGI) and identify risk genes by recognizing gen...

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Detalles Bibliográficos
Autores principales: Shi, Weiwen, Chen, Mengke, Pan, Tingting, Chen, Mengjie, Cheng, Yongjun, Hao, Yimei, Chen, Sheng, Tang, Yuanjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628159/
https://www.ncbi.nlm.nih.gov/pubmed/37932299
http://dx.doi.org/10.1038/s41598-023-44705-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628159/
https://www.ncbi.nlm.nih.gov/pubmed/37932299
http://dx.doi.org/10.1038/s41598-023-44705-3

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