A novel pathway of levodopa metabolism by commensal Bifidobacteria

The gold-standard treatment for Parkinson’s disease is levodopa (L-DOPA), which is taken orally and absorbed intestinally. L-DOPA must reach the brain intact to exert its clinical effect; peripheral metabolism by host and microbial enzymes is a clinical management issue. The gut microbiota is altere...

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Detalles Bibliográficos
Autores principales: Cirstea, M. S., Creus-Cuadros, A., Lo, C., Yu, A. C., Serapio-Palacios, A., Neilson, S., Appel-Cresswell, S., Finlay, B. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628163/
https://www.ncbi.nlm.nih.gov/pubmed/37932328
http://dx.doi.org/10.1038/s41598-023-45953-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628163/
https://www.ncbi.nlm.nih.gov/pubmed/37932328
http://dx.doi.org/10.1038/s41598-023-45953-z

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