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A novel pathway of levodopa metabolism by commensal Bifidobacteria
The gold-standard treatment for Parkinson’s disease is levodopa (L-DOPA), which is taken orally and absorbed intestinally. L-DOPA must reach the brain intact to exert its clinical effect; peripheral metabolism by host and microbial enzymes is a clinical management issue. The gut microbiota is altere...
Autores principales: | Cirstea, M. S., Creus-Cuadros, A., Lo, C., Yu, A. C., Serapio-Palacios, A., Neilson, S., Appel-Cresswell, S., Finlay, B. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628163/ https://www.ncbi.nlm.nih.gov/pubmed/37932328 http://dx.doi.org/10.1038/s41598-023-45953-z |
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