A randomised Phase IIa trial of amine oxidase copper-containing 3 (AOC3) inhibitor BI 1467335 in adults with non-alcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH) is a progressive, inflammatory liver disease with no approved pharmacological treatment. This Phase IIa, double-blind, placebo-controlled, multicentre trial (ClinicalTrials.gov: NCT03166735) investigated pharmacodynamics and safety of BI 1467335, an amine oxidase...

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Detalles Bibliográficos
Autores principales: Newsome, Philip N., Sanyal, Arun J., Neff, Guy, Schattenberg, Jörn M., Ratziu, Vlad, Ertle, Judith, Link, Jasmin, Mackie, Alison, Schoelch, Corinna, Lawitz, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628239/
https://www.ncbi.nlm.nih.gov/pubmed/37932258
http://dx.doi.org/10.1038/s41467-023-42398-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628239/
https://www.ncbi.nlm.nih.gov/pubmed/37932258
http://dx.doi.org/10.1038/s41467-023-42398-w

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