Enzymatic β-elimination in natural product O- and C-glycoside deglycosylation

Biological degradation of natural product glycosides involves, alongside hydrolysis, β-elimination for glycosidic bond cleavage. Here, we discover an O-glycoside β-eliminase (OGE) from Agrobacterium tumefaciens that converts the C3-oxidized O-β-d-glucoside of phloretin (a plant-derived flavonoid) in...

Descripción completa

Detalles Bibliográficos
Autores principales: Bitter, Johannes, Pfeiffer, Martin, Borg, Annika J. E., Kuhlmann, Kirill, Pavkov-Keller, Tea, Sánchez-Murcia, Pedro A., Nidetzky, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628242/
https://www.ncbi.nlm.nih.gov/pubmed/37932298
http://dx.doi.org/10.1038/s41467-023-42750-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628242/
https://www.ncbi.nlm.nih.gov/pubmed/37932298
http://dx.doi.org/10.1038/s41467-023-42750-0

Ejemplares similares