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Disrupting cellular memory to overcome drug resistance

Gene expression states persist for varying lengths of time at the single-cell level, a phenomenon known as gene expression memory. When cells switch states, losing memory of their prior state, this transition can occur in the absence of genetic changes. However, we lack robust methods to find regula...

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Detalles Bibliográficos
Autores principales: Harmange, Guillaume, Hueros, Raúl A. Reyes, Schaff, Dylan L., Emert, Benjamin, Saint-Antoine, Michael, Kim, Laura C., Niu, Zijian, Nellore, Shivani, Fane, Mitchell E., Alicea, Gretchen M., Weeraratna, Ashani T., Simon, M. Celeste, Singh, Abhyudai, Shaffer, Sydney M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628298/
https://www.ncbi.nlm.nih.gov/pubmed/37932277
http://dx.doi.org/10.1038/s41467-023-41811-8