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Disrupting cellular memory to overcome drug resistance
Gene expression states persist for varying lengths of time at the single-cell level, a phenomenon known as gene expression memory. When cells switch states, losing memory of their prior state, this transition can occur in the absence of genetic changes. However, we lack robust methods to find regula...
Autores principales: | Harmange, Guillaume, Hueros, Raúl A. Reyes, Schaff, Dylan L., Emert, Benjamin, Saint-Antoine, Michael, Kim, Laura C., Niu, Zijian, Nellore, Shivani, Fane, Mitchell E., Alicea, Gretchen M., Weeraratna, Ashani T., Simon, M. Celeste, Singh, Abhyudai, Shaffer, Sydney M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628298/ https://www.ncbi.nlm.nih.gov/pubmed/37932277 http://dx.doi.org/10.1038/s41467-023-41811-8 |
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