Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analyses

BACKGROUND: Drug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR) and then validate the candidate drugs using population-based analyses. METHODS: We i...

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Detalles Bibliográficos
Autores principales: Zhang, Naiqi, Li, Yanni, Sundquist, Jan, Sundquist, Kristina, Ji, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628347/
http://dx.doi.org/10.1016/j.ebiom.2023.104859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628347/
http://dx.doi.org/10.1016/j.ebiom.2023.104859

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