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Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analyses
BACKGROUND: Drug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR) and then validate the candidate drugs using population-based analyses. METHODS: We i...
Autores principales: | Zhang, Naiqi, Li, Yanni, Sundquist, Jan, Sundquist, Kristina, Ji, Jianguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628347/ http://dx.doi.org/10.1016/j.ebiom.2023.104859 |
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