Inference of differential key regulatory networks and mechanistic drug repurposing candidates from scRNA-seq data with SCANet

MOTIVATION: The reconstruction of small key regulatory networks that explain the differences in the development of cell (sub)types from single-cell RNA sequencing is a yet unresolved computational problem. RESULTS: To this end, we have developed SCANet, an all-in-one package for single-cell profilin...

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Detalles Bibliográficos
Autores principales: Oubounyt, Mhaned, Adlung, Lorenz, Patroni, Fabio, Wenke, Nina Kerstin, Maier, Andreas, Hartung, Michael, Baumbach, Jan, Elkjaer, Maria L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628438/
https://www.ncbi.nlm.nih.gov/pubmed/37862243
http://dx.doi.org/10.1093/bioinformatics/btad644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628438/
https://www.ncbi.nlm.nih.gov/pubmed/37862243
http://dx.doi.org/10.1093/bioinformatics/btad644

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